How about The Curious Incident of the Dog in the Night-time
by Mark Haddon? You guys may have read it already....I'm a little behind in some of my reading.
"...is a murder mystery of sorts--one told by an autistic version of Adrian Mole. Fifteen-year-old Christopher John Francis Boone is mathematically gifted and socially hopeless, raised in a working-class home by parents who can barely cope with their child's quirks. He takes everything that he sees (or is told) at face value, and is unable to sort out the strange behavior of his elders and peers."