I went to a cosmetic surgeon last month and he told me that he tells most of his patients to use Retin-A. I told him that it irritated and dried out my skin. He said most people use too much of it and don't go slow with it. He said to use a pea size amount and dab all over your face then rub it in. He said to start out using it once a week and slowly increase it to everynight. I also read that you can put it over your moisturizer at night.