I started taking Cymbalta and tried Lyrica several years ago for depression, fibromayalgia, and neuropathy. . . Unfortunately, My hair went from shiny, thick, wavy hair to the most ugly curls I've ever seen, now my hair is brittle and so frizzy, it's not worth the time and products to try and straighten it. Odd thing is that my hair is still straight in one small row underneath by my neckline. I am still on Cymbalta and probably will be for life so I don't see this irritating problem going away anytime soon!!