I've known five or six people who've taken it, none with serious side effects, and all with significant and long-lasting improvement in acne. This includes both my sons, one of whom is also hypothyroid and on meds. Topicals and antibiotics had very little improvement for either of them (facial and extensive back/chest acne), so accutane was our last resort. They had the usual dry skin/chapped lips, but no hair thinning. For them, their acne was 100% gone and has remained so except for the occasional small spot for nearly six years for the elder and four years for the younger. Both were monitored very carefully while on it. I wouldn't recommend it for mild acne, but it does work and usually does last.
3a/b, fine, normal porosity, high density

Wash: CJ Daily Fix, As I Am, TJs TTT
RO: YTB
LI: Suave TC + CJ CCCC, brushed through with Denman
Styling: Smooth in LAL Wet Look gel, scrunch, and plop 10 minutes, then add a little more gel, cover with silk cap, and sleep on it
Refresh: 3:1 water/Suave mix as needed