I've done a few rounds of low dose
I did one round of regular/high dose, about 20 years ago, and it stopped the cystic acne in its track. Since then, I've started and usually stopped because of unrelated health issues, a couple of rounds of LOW dose Accutane. Amazing results, but I usually only stay clear for about 2 years afterwards (still, much better than originally).
My lips were dry, my eyes felt dry, but that's about it in terms of side effects.
I am planning to go on a low dose, starting in the Fall (away from the summer sun) - hopefully this will be my last round! I tend to be forgetful in taking the medications, esp when I get clear relatively quickly.
I wish that I had started on Accutane in my teen years and am thankful that it is in our arsenal for my daughters, as acne can be so damaging, physically and emotionally.
Growing out a pixie (last big cut July 2012)
3a? 3b? Fine, dense. Porous.
Finally sulfate free. Avoiding silicones.