I am a little confused on the optimized issue. My dose of 90 mg is only 1 grain? I take 3 pills a day for this dose, each of which is 30 mg. I am seeing my GP tomorrow for the bloodwork and he is not progressive. He only goes by the tsh levels and lives and breathes Synthetic. I went to an endo, without his approval, and got the Armour. He just shook his head. I want to have bloodwork for cholestrol, sugar, c-reactive protein, and other general workup, to see if I hav anything else going on. We will talk about the thyroid, but I will probably have to go back to the endo to get any results. Did you take any of the synthetic thyroid previously?