Rhogam

I have O- blood and DH is +, so it's been recommended that I get the Rhogam shot around 28 weeks pregnant. My midwives say the blood type difference is unlikely to affect this pregnancy, which is why it's "recommended" and not something they make you do (I know they can't actually make you, just making a point). Anyway, some things I've read definitely recommend it more strongly than others. Anyone have experience with this? Are there any negative effects to doing it, other than an extra shot (which isn't a big deal)?
I had the shots at 28 weeks and after the birth of all three of my children. I'm A- my husband is B+. All of my kids are +. I took the shots because I figured it was better to be safe than sorry. I've not had much luck with pregnancies to begin with. I never had any issues with the shots.
I had it twice and had no side effects.
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I had it twice and had no side effects.
Originally Posted by nynaeve77
Did you have it during pregnancy (at 28 weeks) or after delivery?
It will not affect this pregnancy because you haven't given birth yet, and there hasn't been a chance for the babies blood to mix with your blood. Not getting the shot may however, affect your next pregnancy.

The shot prevents, in the event of the blood mixing, that your body will see the baby's blood as a virus, and build up antibodies to fight it.

Because there is a possibilty of having opposite blood types, during birth, there's a chance of the baby's blood mixing with yours. If this happens your body will see the blood as a virus and will build up antibodies to fight it. What happens then is the next time you get pregnant, if your baby has a postive blood type, your body will recognize it as a threat and possibly fight the baby as it is a virus.

In the past, before the Rhogam shot the first baby would be fine, but every subsequent baby would sometimes have little health problems, each baby being worse than the one before.

- this is what I know of being RH negative. I'm not a medical professional. I'm RH negative myself and had shots with both of my children.
It will not affect this pregnancy because you haven't given birth yet, and there hasn't been a chance for the babies blood to mix with your blood. Not getting the shot may however, affect your next pregnancy.

The shot prevents, in the event of the blood mixing, that your body will see the baby's blood as a virus, and build up antibodies to fight it.

Because there is a possibilty of having opposite blood types, during birth, there's a chance of the baby's blood mixing with yours. If this happens your body will see the blood as a virus and will build up antibodies to fight it. What happens then is the next time you get pregnant, if your baby has a postive blood type, your body will recognize it as a threat and possibly fight the baby as it is a virus.

In the past, before the Rhogam shot the first baby would be fine, but every subsequent baby would sometimes have little health problems, each baby being worse than the one before.

- this is what I know of being RH negative. I'm not a medical professional. I'm RH negative myself and had shots with both of my children.
Originally Posted by iroc
Thanks -- I know pretty much how it works; there's also a small chance that baby's blood will mix with mine during this pregnancy. DH is going to get his blood type tested just to make sure of what it is at my next appointment (next week). His mom couldn't remember when I asked, just that hers and FIL's are +, so good chance his is positive too. I guess I'll talk to my midwife more after that and go from there.
I had it twice and had no side effects.
Originally Posted by nynaeve77
Did you have it during pregnancy (at 28 weeks) or after delivery?
Originally Posted by Like.Australia
During pregnancy.
"Maybe Lucy's right. Of all the Charlie Browns in the world, you're the Charlie Browniest."--Linus, A Charlie Brown Christmas
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My fotki: http://public.fotki.com/nynaeve77/
Password: orphanannie
I had it twice and had no side effects.
Originally Posted by nynaeve77
Did you have it during pregnancy (at 28 weeks) or after delivery?
Originally Posted by Like.Australia
During pregnancy.
Originally Posted by nynaeve77
Thanks. Makes me feel better to hear from others who've had it.

My in-laws reaction to my asking about it was, "Ohhhh you have one of those weird blood types..." Yes, weird. Thanks.
I'm O-, too...we're universal donors!
"Maybe Lucy's right. Of all the Charlie Browns in the world, you're the Charlie Browniest."--Linus, A Charlie Brown Christmas
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My fotki: http://public.fotki.com/nynaeve77/
Password: orphanannie
For the record, I was given my shot during, and after pregnancy.

I'm A- and both my children are A+
I'm O-, too...we're universal donors!
Originally Posted by nynaeve77
Yep. They're not the most knowledgable people on the subject.
For the record, I was given my shot during, and after pregnancy.

I'm A- and both my children are A+
Originally Posted by iroc
Did they do the shot after pregnancy after checking baby's blood type or did they automatically do it? Was it immediately after delivery or at a later checkup?
For the record, I was given my shot during, and after pregnancy.

I'm A- and both my children are A+
Originally Posted by iroc
Did they do the shot after pregnancy after checking baby's blood type or did they automatically do it? Was it immediately after delivery or at a later checkup?
Originally Posted by Like.Australia


They did the one at the 28 week checkup, and again within 24 hours of the birth of the baby.

I can't remember if this was because they had checked the blood type because they did it the next day, and both babies were positive anyway so I would have needed it.
Rhogam is very safe, for both you and your baby. Your future babies will do better because you proactively worked to decrease the formation of antibodies during this pregnancy that might cause harm in the next. Rhogam isn't new...it's been around for 40-50 years, and has proven to be both effective and safe.

You really don't want to risk rhesus disease with future pregnancies.
For the record, I was given my shot during, and after pregnancy.

I'm A- and both my children are A+
Originally Posted by iroc
Did they do the shot after pregnancy after checking baby's blood type or did they automatically do it? Was it immediately after delivery or at a later checkup?
Originally Posted by Like.Australia
I was given my second shot with both of my kids after the baby's blood was tested. I am A- and both of the kids are A+ like my husband. It was immediately after delivery with both of them.


I had Rhogam during my pregnancy, after my delivery, and after a MC. It has no side effects, will not hurt the baby, and will protect any future pregnancies. My mother had Rhogam when she was delivering all her kids and told me that I would need it when I had children. I never thought of not taking it. I want to protect my ability to have more children, benefits WAY outweigh any risks.
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Well I whacked into our granite counter top last night and woke up with a bruise on my side this morning. I called my midwife to ask her what, if anything, I should do and she said she usually advises that if it still hurts the next day (a bump to the abdomen), o- women should get the rhogam shot ASAP. Sooo.. Off to the ER I went. All rhogamed up for now!


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I'm O-, husband is O+. I don't remember getting rhogam during pregnancy but I could be wrong. I definitely got it after both kids and after 1 miscarriage in between. My first son is O- like me, second one is O+. They gave me the shot before they knew baby's blood type. There were no negatives to getting it. I would do again without hesitation.
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