I've had issues with polyquats twice. The first time was biotera gel and I couldn't figure out what was wrong with my hair other than it was terrible and kept getting worse. I had to use a sulfate shampoo twice to fix it. This morning I tried HESMU. I knew as it was putting it on my hair it wasn't going to work. It dried all tangly and nasty. I had to wash again with sulfate shampoo. No more polyquats for me. Especially number four.