I used Premarin for about three years but stopped when the report came out about the adverse effects. I did use hormones in patch form for about a year after that, because the night sweats were so bad then that I was getting zero sleep. Some people theorize that hormones in patch form have fewer of the bad effects of oral HRT because they are not metabolized through the liver. (I used "Combi-Patch.")

I've seen some research lately saying that women who use hormones for a few years right after menopause are not likely to have harmful effects. Hope they're right!